Pulling to the protease

utrition and cell death are integrated in a single mitochondrial complex, according to Nika Danial, Stanley Korsmeyer (Harvard Medical School, Boston, MA), and colleagues. The complex was discovered after gel filtration of the pro-apoptotic BAD protein, and contains BAD, a phosphatase, kinase, and kinase-anchoring protein directed at BAD, and glucokinase. In cells lacking BAD, the complex falls apart, respiration is compromised, and blood glucose regulation is abnormal. A nonphosphorylatN